Test & Collection Guide

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Anti RNA polymerase 3

Ordering information:

Relevant clinical details.

Alternate names:
anti RNA Pol III, anti RNA Polymerase III
Referred Test
Specimen types:
Container types:
Serum tube with gelSerum tube with gel
Collection Instructions:
Transport specimen at Room Temperature to lab
Sample haemolysis may make this test unreportable
Minimum Adult Volume:
2 mL
Paediatric Minimum Volume:
0.5 mL
Reference Interval:

Results : Negative / Weak positive / Positive 

Laboratory Use Only
Storage Instructions:

No special  instructions - per St Vincents

Transport Instructions:

No special  instructions - per St Vincents

Laboratory Notes:

Anti RNA Polymerase III may be useful in the investigation of Systemic Sclerosis and may indicate a hightened risk of renal involvement.

Systemic Sclerosis is a rare autoimmune disorder characterised by the presence of various auto antibodies including anti centromere, anti topoisomerase (Scl70) anti PM/Scl-100 and anti RNA Polymerase III ( RNA Pol III ).

The St Vincents assay is performed when they have enough to make a batch which is usually fortnightly.

25.3.11 CR

External Laboratory:
St Vincents Hospital
 External Laboratory details...