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Recent changes for Tryptase
Mast Cell - Tryptase
Tryptase
Mast Cell Tryptase
0.5 mL
Stable 48 hours refrigerated, transport frozen if unable to ensure delivery of sample to the Alfred within 48 hours of collection. .
Separate serum and store frozen - 20 degrees.
Spin, separate and freeze serum if unable to ensure delivery of sample to the Alfred within 48 hours of collection. .
Spin, separate and freeze serum
Alfred Hospital
St Vincents Hospital
Weekly
Fortnightly
For investigation of anaphylaxsis send both acute (e.g. initial ED bloods) and follow up (e.g. after clinical improvement) samples if possible.
Increased levels of Tryptase can be detected up to 3 to 6 hours after the anaphylactic reaction. Levels return to normal within 12 to 24 hours after release. For investigation of anaphylaxis recommends sampling for tryptase at 1 hour, 4 hours and 24 hours post onset of reaction. Baseline serum tryptase is also used for the investigation of mastocytosis and other mast cell discorders. Please note that non-specific Tryptase elevation can also occur in end stage renal failure, severe asthma, cardiac arrest, post-CPR or in the post-mortem period. Clinical correlation recommended.
Increased level of tryptase can normally be detected up to 3 to 6 hours after the anaphylactic reaction. Levels return to normal within 12-14 hours after release.
0.0 -11.4 ug/L
41 Victoria Parade,
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