Test & Collection Guide

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Light Chains - Serum

Alternate names:
FLC, Free light chains
Test Code:
Specimen types:
Container types:
Plain Tube with gelPlain Tube with gel
Collection Instructions:
Transport specimen at Room Temperature to lab
Sample haemolysis may make this test unreportable
Minimum Adult Volume:
2 mL
Paediatric Minimum Volume:
1 mL
Twice weekly
Result Turnaround Time:
4-5 days
Reference Interval:

Kappa Free LC       3.3-19.4 mg/L

Lambda Free LC    5.7- 26.3 mg/L

K/L Ratio                 0.26-1.65

Laboratory Use Only
Storage Instructions:

Light Chain detection - The presence of free and intact monoclonal light chains is assessed by immunofixation after electrophoresis or isoelectric focusing or serum free light chains may be measured by immunoassay.

Light Chain typing - The heavy and light chain classes are determined when a new monolconal protein (paraprotein) has been detected in a previously undiagnosed patient.

Consult with Pathology staff regarding possible further studies.