Pathology

Test & Collection Guide

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Light Chains - Serum

Alternate names:

FLC, Free light chains

Laboratory:

Biochemistry

Test Code:

FLC

Specimen types:

Serum

Container types:

Serum tube with gel

Collection Instructions:

Transport specimen at Room Temperature to lab
Sample haemolysis may make this test unreportable

Minimum Adult Volume:

2 mL

Paediatric Minimum Volume:

1 mL

Frequency:

Twice weekly

Result Turnaround Time:

4-5 days

Reference Interval:

Kappa Free LC 3.3-19.4 mg/L

Lambda Free LC 5.7- 26.3 mg/L

K/L Ratio 0.26-1.65

Laboratory Use Only

Storage Instructions:

Light Chain detection - The presence of free and intact monoclonal light chains is assessed by immunofixation after electrophoresis or isoelectric focusing or serum free light chains may be measured by immunoassay.

Light Chain typing - The heavy and light chain classes are determined when a new monolconal protein (paraprotein) has been detected in a previously undiagnosed patient.

Consult with Pathology staff regarding possible further studies.