Pathology

Test & Collection Guide

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TORCH Serology

Ordering information:

In EMR- Request individual tests

Toxoplasma, Rubella, CMV and Herpes serology

Alternate names:

TORCH, TORCH screen

Laboratory:

Microbiology

Test Code:

TORCH

Specimen types:

Serum

Container types:

Serum tube with gel

Collection Instructions:

Sample haemolysis may make this test unreportable
Transport specimen at Room Temperature to lab

Screen includes - Toxoplasmosis, Rubella, CMV and Herpes Simplex

Notes:

	Toxoplasmosis	Rubella	CMV	Herpes simplex
At risk if:	Maternal symptoms or IgM positive	Maternal primary infection or re-infection	Maternal primary infection (50%) Maternal reinfection or reactivation (?1%)	Maternal genital infection in pregnancy (recurrent, acquisition of other type if already infected, initial non-primary, primary)
Initial tests - maternal serology	Maternal IgG positive and IgM negative: No further action required. Maternal IgM + IgG positive: Request neonatal testing.	Maternal rubella IgG/IgM if (i) contact with rubella (ii) rubella-like illness	Maternal IgG &/or IgM positive: Request neonatal testing	Clinical assessment, antenatal serology or viral PCR results if available
Neonatal testing if indicated by maternal results and clinical suspicion	Serology ? IgG & IgM PCR ? blood*, CSF	Serology ? rubella IgM PCR ? urine, throat swab, tears (conjunctival swab), lens tissue (if available)	Serology ? CMV IgM PCR ? blood*, urine, saliva	PCR ? surface swabs (eye, throat, umbilicus, rectum), urine, blood*, CSF if positive surface swabs or infant with clinical illness

Frequency:

Daily

Result Turnaround Time:

2-7 days

Reference Interval:

Toxoplasma, Rubella, CMV performed daily at BHH (adults)

HSV performed weekly at RCH.

Laboratory Use Only

Laboratory Notes:

On adults,Toxo, CMV & rubella performed at BHH, HSV send to RCH.

If requested on a baby, DO NOT perform any testing at EHP. Do not add Rubella IgG.

Refer the specimen to Microbiology, who will send to RCH to do ALL the testing, including Rubella IgM.

If minimal sample, send all to RCH, Microbial Serology . Contact 9345 4910.

External Laboratory:

Royal Childrens Hospital

External Laboratory details...