Pathology

Test & Collection Guide

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Homocysteine - L-methionine Loading

Laboratory:

Biochemistry

Test Code:

HCYPR, HCYPO

Specimen types:

Plasma

Container types:

EDTA
Lithium heparin no gel

Notes:

Patient (if outpatient) must make a booking with collection staff so that L-methionine can be organised with pharmacy.

PATIENT INSTRUCTIONS FOR HOMOCYSTEINE TEST

First Sample

Is a fasting sample. This requires fasting from midnight prior to the day of your test

Second sample

Is collected 6 hours after you have ingested a drink containing L- methionine to be taken immediately.

Note: some side effects may be noted taking L-methionine eg dizziness, nausea. If patients experience any side effects they are advised not to drive.

Fasting Plasma sample is required

Pre :

1 EDTA tube on ice or to laboratory immediately (within 30 minutes)

1 Lithium Heparin tube (no gel) - do NOT spin, wrap in foil immediately

1 plain tube - wrap in foil immediately

Give L-methionine mixed with orange juice

Post :

Specimen to be taken 6 hours after ingestion of L-methionine.

The time is important.

Take 1 EDTA tube on ice or immediately to the laboratory (within 30 minutes)

Frequency:

Weekly

Result Turnaround Time:

7 days