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Test & Collection Guide

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Renin - plasma

Laboratory:
Biochemistry
Test Code:
REN
Specimen types:
Plasma
Container types:
EDTA
EDTA - Paediatric
EDTA
Collection Instructions:

Collection Requirements

Collect into a 4 mL EDTA tube at Room Temperature. Do not collect on ice

If both Renin and Aldosterone are requested together, they can be collected into the same EDTA tube.

Renin is stable in whole blood for up to 6 hours at room temperature.

In the laboratory, spin and separate the plasma. Plasma is stable at Room Temperature for up to 2 days. 

Renin must be frozen at -70 C if unable to test within 2 days at the Box Hill Laboratory. 

Transport plasma at room temperature.

Add-on tests for Renin should not be done on samples which have been previously collected or stored at 4 C.

Minimum Adult Volume:
1 mL
Notes:

Prior to testing, patients should be withdrawn from diuretics, ACE inhibitors, angiotensin II receptor antagonists, beta blockers and calcium channel blockers for 3 weeks. Ideally, patients should also be well hydrated, have had 7g/day of salt for one week and have normal plasma potassium and bicarbonate levels.

 Deliver to laboratory at room temperature

Frequency:
Weekly
Result Turnaround Time:
4-7 days
Reference Interval:

 

Upright

4.4 – 46.1 mIU/L

Supine

2.8 – 39.9 mIU/L

 

Laboratory Use Only
Storage Instructions:

 

Minimum plasma volume: 500 ul (1mL if aldosterone is also requested)