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Lupus Anticoagulant Screen

Alternate names:
LA, LAC
Laboratory:
Coagulation
Test Code:
LAS
Specimen types:
Plasma
Container types:
Sodium CitrateSodium Citrate
Collection Instructions:

Notification of anticoagulant therapy is essential

Two (2x) Sodium citrate tubes required. Do not use 1 ml citrate tubes.

Filled to label marker and mixed by inversion

The patient must not be receiving heparin

Transport to laboratory immediately.

Tests performed:

INR, APTT, APTT Mix, Lupus sensitive APTT and Dilute Russell's Viper venom time (LA screen/Confirm).

 

Frequency:
Weekly
Result Turnaround Time:
2 weeks
Reference Interval:

LA screen   <1.2 Lupus anticoagulant not detected.

LA Confirm <1.2 Lupus anticoagulant not detected

                    1.2 - 1.5 L.A. weakly present

                    1.5 - 2.0 L.A. moderately present.

                     >2.0      L.A. strongly present

                                                

Laboratory Use Only
Laboratory Notes:

Centrifuge the two 3.5 mL citrate tubes and transfer the plasma to a labeled 4 mL plastic tube and re-centrifuge at room temperature (do not use the refrigerated centrifuge).

The double centrifuged plasma is transferred to two 1 mL eppendorf tubes and freeze.