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Anti-Liver-Kidney Microsomal Antibodies

Alternate names:
LKM
Laboratory:
Referred Test
Test Code:
LKMIC
Specimen types:
Serum
Container types:
Serum tube with gelSerum tube with gel
Collection Instructions:
Transport specimen at Room Temperature to lab
Sample haemolysis may make this test unreportable
Minimum Adult Volume:
2 mL
Paediatric Minimum Volume:
1 mL
Frequency:
Weekly
Result Turnaround Time:
7-10 days
Reference Interval:

< 10 (Titre)

Laboratory Use Only
Transport Instructions:

Transport at 4oC

Laboratory Notes:

Liver disease or Hepatitis of unknown aetiology may raise the possibility of Autoimmune Hepatitis. Indications for testing are negative viral serology and elevated transaminases. There are various subtypes of autoimmune hepatitis – different antibody patterns can help categorise the subtypes.

Tests requested could include:

ANA , Anti Nuclear Antibody

SMA, Smooth Muscle antibody

LKM, Liver Kidney Microsome 1

ANCA, Anti Neutrophil Cytoplasmic Antibody (esp. perinuclearANCA )

SLA, Soluble Liver antigen

SLA/LP, Soluble Liver antigen and/or Liver pancreas antibody

LCA, Liver Cytosol antibodies

LSMP, Liver specific membrane lipoprotein antibody

 

6.4.11 CR

External Laboratory:
St Vincents Hospital
 External Laboratory details...