Pathology

Test & Collection Guide

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Anti-Thyroid Peroxidase Antibodies

Alternate names:

Anti-Thyroid Microsomal Antibodies, Anti-TPO Antibodies

Laboratory:

Biochemistry

Test Code:

THYM

Specimen types:

Serum

Container types:

Serum tube with gel

Collection Instructions:

Transport specimen at Room Temperature to lab
Sample haemolysis may make this test unreportable

Minimum Adult Volume:

2 mL

Paediatric Minimum Volume:

1 mL

Frequency:

Twice weekly

Result Turnaround Time:

4 days

Reference Interval:

<34 IU/mL

Laboratory Use Only

Storage Instructions:

Thyroid Peroxidase (TPO) has been cloned from thyroid microsomes and identified as the primary antigen in 'Anti-Thyroid Microsomal Antibodies'

Levels are elevated in almost all cases of Hashimoto's thyroiditis and in the majority of Graves' disease patients (Anti-TSH Receptor Antibody is more specific for Graves' disease)