Services

Test & Collection Guide

Pathology staff view

 New search...

Keyword Search:

Test name:

  

Manual search:

PLEASE NOTE: Recent changes have been made to this Test


 Recent changes for Imatinib Level

Recent changes for Imatinib Level

Date
Field
Changed From
Changed To
4th April 2019
Request Group

IMAT

14th February 2019
Processing Instructions

Spin,aliquot plasma and freeze.

External Transport Instructions

Frozen sample to be packed by IATA trained personal.

Imatinib Level

Ordering information:

Collect sample just before next dose (trough sample).

NOTE: date,time and amount of last dose must be provided on the request form for result interpretation.

Alternate names:
Glivec
Laboratory:
Referred Test
Test Code:
IMAT
Specimen types:
Plasma
Container types:
EDTAEDTA
Collection Instructions:

Collect sample just before next dose (trough sample).

Minimum Adult Volume:
2 mL
Frequency:
As required
Result Turnaround Time:
4 weeks
Reference Interval:

A recent study demonstrated that trough (sample taken just before the next dose) imatinib plasma concentrations were associated with cytogenetic and molecular response in CML. A patient with trough imatinib plasma concentration >1000 ng/ml is 8 times more likely to experience a therapeutic effect compared with patients who have concentrations below this effect target. Furthermore,GIST patients with a trough imatinib plasma concentration <1100 ug/L had lower rates of clinical benifit and faster time to progression. A target for toxicity has not been defined;however,fluid retension,rash,myalgia and anaemia apper to be common at higher imatinib concentrations.

Suggested target for effect in CML is >1000 ug/L

Suggested target for effect in GIST is >1100 ug/L

Toxicity: monitor patient carefully if trough imatinib plasma concentration exceeds 2000 ug/L

Laboratory Use Only

SPECIMEN COLLECTION MODULE (SCM) FAQs - CLICK HERE

 

CLICK HERE for a consent form to perform tests not covered by Medicare

TURN AROUND TIMES - When will my result be available?

CLICK HERE for Minimum Labelling Requirements

CLICK HERE for a printable Pathology request form

CLICK HERE for a Log sheet for recording Pathology results

"THE ART OF CCCCOLLECTION"

PLEASE CLICK HERE FOR THE PREFERRED ORDER OF DRAW