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PLEASE NOTE: Recent changes have been made to this Test
Recent changes for Thiopurine Metabolites
Recent changes for Thiopurine Metabolites |
Date | Field | Changed From | Changed To |
| 3rd March 2023 | Preferred Container Type | Lithium heparin no gel
EDTA | See Instructions |
| 25th August 2022 | Collection & Request Instructions | Collect 1 x 4 ml Lithium Heparin tube and
1 x 4ml EDTA tube.
FBE must be requested with this test as a RCC is required for calculation of results
DO NOT SPIN.
Keep at Room Temp.
| Collect 1 x 4 ml Lithium Heparin tube and
2 x 4ml EDTA tube.
FBE must be requested with this test as a RCC is required for calculation of results
DO NOT SPIN.
Keep at Room Temp.
|
| 23rd August 2022 | Collection & Request Instructions | Collect 1 x 4 ml Lithium Heparin tube and 1 x 4ml EDTA tube.
FBE must be requested with this test as a RCC is required for calculation of results
DO NOT SPIN.
Keep at Room Temp.
| Collect 1 x 4 ml Lithium Heparin tube and
1 x 4ml EDTA tube.
FBE must be requested with this test as a RCC is required for calculation of results
DO NOT SPIN.
Keep at Room Temp.
|
| 23rd August 2022 | Request Group | | TMETAB |
| Preferred Container Type | EDTA | Lithium heparin no gel
EDTA |
| Collection & Request Instructions | | Transport specimen at Room Temperature to lab |
| Collection & Request Instructions | Collect 2x4ml EDTA blood. DO NOT SPIN
Keep at 4 deg C, do not freeze.
The metabolites are stable for upto 4 days at 4 degress. | Collect 1 x 4 ml Lithium Heparin tube and 1 x 4ml EDTA tube.
FBE must be requested with this test as a RCC is required for calculation of results
DO NOT SPIN.
Keep at Room Temp.
|
| Processing Instructions | | Keep samples at Room Temperature.
Do Not Spin. Whole Blood required |
| External Laboratory | | St Vincents Hospital |
| Frequency | | Weekly |
| Notes | Imuran is a trade name for azathioprine
The Thiopurine metabolites (6-TGN & 6-MMP) are used as a means of estimating the toxicity and efficacy of azathioprine treatment.
This test is performed by the Gastroenerology department. ( Phone No.9895 4632 )
The cost for the test is not covered by Medicare.
Eastern Health patients:6TGN 6MMP Thiopurine Metabolites Testing $75
All other patients: 6TGN 6MMP Thiopurine Metabolites Testing $145 | Imuran is a trade name for azathioprine
The Thiopurine metabolites (6-TGN & 6-MMP) are used as a means of estimating the toxicity and efficacy of azathioprine treatment.
|
Thiopurine Metabolites |
Ordering information: | Test requires a dedicated Lithium Heparin and EDTA sample.
Collect 1 x 4 ml Lithium Heparin tube and
2 x 4ml EDTA tube.
A FBE must also be performed.
|
Alternate names: | 6MMP, 6TG, AZA metabolites, Imuran Metabolites |
Laboratory: | Referred Test |
Test Code: | TMETAB |
Specimen types: | Blood |
Container types: | | See Instructions |  |
|
Collection Instructions: | Transport specimen at Room Temperature to lab
Collect 1 x 4 ml Lithium Heparin tube and
2 x 4ml EDTA tube.
FBE must be requested with this test as a RCC is required for calculation of results
DO NOT SPIN.
Keep at Room Temp.
Li Hep and EDTA must be sent to St Vincent's Pathology together
|
Minimum Adult Volume: | 8 mL |
Notes: | Imuran is a trade name for azathioprine
The Thiopurine metabolites (6-TGN & 6-MMP) are used as a means of estimating the toxicity and efficacy of azathioprine treatment.
|
Frequency: | Weekly |
Result Turnaround Time: | 2 weeks |
Reference Interval: | 6TGN: 235 - 450
6MMP: 250 - 5700 |
Laboratory Use Only |
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