Every synacthen test must have cortisol measured on all 3 serum tubes.
See ACTH instructions for processing of EDTA sample. (collect onto Ice and send immediately to the laboratory)
If the synacthen test is for " Congenital Adrenal Hypoplasia"/"CAH", Each serum sample must also have 17-hydroxyprogesterone (in addition to cortisol ) measured.
Endocrine consultation is suggested for Long synacthen Test.
The Short Synacthen Test may be requested in the investigation of patients for "Addison's disease", "Adrenal failure" or Congenital Adrenal Hypoplasia" (CAH).
The test involves IM/IV administration of 250 micrograms of synacthen (synthetic ACTH) by an appropriate clinician.