Do not request if patient is on an ACE inhibitor.

CSF ACE has poor sensitivity and specificity hence it will no longer be referred.

Preferable to receive a fasting sample.

Transport to laboratory on ice or transport immediately to laboratory and contact the laboratory staff to expect the sample.

Patients on ACE inhibitor drugs will have reduced values.

Serum ACE levels are a nonspecific indicator of granulomatous disease.  The ACE level can be normal in up to about 50% of patients with sarcoidosis.

<20 Yrs        29-112 U/L

>20Yrs         20-70 U/L